Product Name: Anib 40mg
Generic Name: Afatinib 40mg
Pack Size: 30’s Tab.Let
Company Name: Drugs Pharmaceutical Ltd
Origin: Bangladesh
Order By Whatsapp +880 1776585142
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Apatinib, also known as rivoceranib, is a tyrosine kinase inhibitor that selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2, also known as KDR). It is an orally bioavailable, small molecule agent which is thought to inhibit angiogenesis in cancer cells; specifically, apatinib inhibits VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. This agent also mildly inhibits c-Kit and c-SRC tyrosine kinases.
EGFR Mutation-Positive, Metastatic Non-Small Cell Lung Cancer: Anib is indicated for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) substitution mutations as detected by an FDA-approved test. Limitation of Use: The safety and efficacy of Anib have not been established in patients whose tumors have other EGFR mutations. Previously Treated, Metastatic Squamous NSCLC: Anib is indicated for the treatment of patients with metastatic squamous NSCLC progressing after platinum-based chemotherapy.
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